Gas chromatographs GC/MS-QP2010 SE with DI, GC/MS QP5050A and GC-2014AFsc
Two flexible quadrupole GC/MS systems of type QP5050A and QP2010SE and one GC with FID (flame-ionization detection) of type GC-2014AFsc from Shimadzu with LabSolutions version 1.2 are used for the gas chromatic separation and analysis. Very high sensitivity down to the low pg-range (fg-range for SIM mode) are achieved using a computer optimized ion source optic and lens system as well as an absolutely oil-free vacuum from a turbo molecular pump (150 l/s). The NIST-, WILEY- and FFNSC- library help to identify the measured mass spectra (between 35 and 900 Dalton).
The auto sampling system HTX PAL from CTC Analytics with headspace optimizes the injection by means of several adjustable parameters. In addition the QP2010SE enables direct sample injection (DI) this allows a sample to be introduced directly into the ion source. It is used for synthetic compounds and samples, which are difficult to vaporize or thermally degradable.
LC/MS liquid chromatograph coupled to mass spectrometer LC 1100 MSD SL
In order to separate and analyze non-volatile organic compounds, use is made of an LC/MS (liquid chromatograph coupled to a mass spectrometer) of the type LC 1100 MSD SL by Agilent. The sample solution is ionized at atmospheric pressure using an electron spray method (API-ES) at fragmentor voltages up to 6000 V and permits quantitative analysis down to the fg region in the case of masses up to 3000 Dalton. In addition to the detection using MS, use is made of a conventional DAD (diode array) and an RI (refractive index) detector. The same instrument design allows GPC (gel permeation) and GFC (gel filtration) analyses for determining the molecular sizes of e.g. polymers and biomaterials.